Search on: NIMA INTERACTING PEPTIDYLPROLYL ISOMERASE 
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Descriptor English:   NIMA-Interacting Peptidylprolyl Isomerase 
Descriptor Spanish:   Peptidilprolil Isomerasa de Interacción con NIMA 
Descriptor Portuguese:   Peptidilprolil Isomerase de Interação com NIMA 
Synonyms English:   PIN1 Protein
Peptidyl-Prolyl Cis-Trans Isomerase Pin1
Pin1 Peptidylprolyl Isomerase
Isomerase, NIMA-Interacting Peptidylprolyl
Isomerase, Pin1 Peptidylprolyl
NIMA Interacting Peptidylprolyl Isomerase
Peptidyl Prolyl Cis Trans Isomerase Pin1
Peptidylprolyl Isomerase, NIMA-Interacting
Peptidylprolyl Isomerase, Pin1  
Tree Number:   D08.811.399.325.500.700
Definition English:   A highly-conserved peptidyl-prolyl cis/trans isomerase (PPIase) that binds to and isomerizes specific phosphorylated SERINE- or THREONINE-PROLINE (pSer/Thr-Pro) motifs and causes conformational changes in certain proteins associated with the CELL CYCLE. It displays a preference for an acidic residue N-terminal to the isomerized proline bond and regulates MITOSIS, possibly by attenuating the mitosis-promoting activity of NIMA-RELATED KINASE 1. 
History Note English:   2017 (1996) 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
CT contraindications DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   56495 
Unique Identifier:   D000072340 

Occurrence in VHL:
 

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